- 询价
- KA&M BIO
- MAB3969
- 2025年07月12日
- IHC,WB
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a, kappa
- 形态：
Liquid
- 保存条件：
at-20℃
- 库存：
99
- 宿主：
Mouse
- 应用范围：
IHC,WB
- 浓度：
见说明
- 抗体英文名：
Anti-Cav3.2 Ca2+ channel Monoclonal antibody (N55/53)
- 规格：
50-100ug
小鼠抗Cav3.2 Ca2+ channel单克隆抗体(克隆号N55/53)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
小鼠抗Cav3.2 Ca2+ channel单克隆抗体(克隆号N55/53)更多优势产品欢迎新老客户选购。
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文献和实验Ca2+ Imaging as a Tool to Assess TRP Channel Function in Murine Distal Nephrons
Transient receptor potential (TRP) channels are expressed in almost every segment of renal nephron from the glomerulus to the inner medullary collecting duct. Serving as a route for Ca2+ entry from the intratubular space into cells
Muscle contraction is affected by the rapid release of Ca2+ ions through Ca2+ - conducting channels localized in an intracellular mem- brane compartment, the sarcoplasmic reticulum (SR). The rabbit skel- etal muscle SR Ca2+ release channel
Measurement of Ca2+ Entry Using 45Ca2+
+ channels under voltage-clamp conditions (2 ); however, Cao 2+ entry into small excitable cells could only be measured using 45 Ca2+ . With the improvement of patch-clamp techniques (3 ), Cao 2+ entry was measured via the analysis of single-channel
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