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- 文献和实验
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- 保存条件:
at-20℃
- 库存:
99
- 抗体英文名:
Anti-Bordetella pertussis fhaB/FHA Monoclonal antibody (T5)
- 规格:
50-100ug
抗Bordetella pertussis fhaB/FHA单克隆抗体(克隆号T5)上海圻明生物优势供应欢迎咨询。配对抗体小课堂:
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.

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文献和实验百日咳杆菌( bordetella pertussis )是人类百日咳的病原菌。百日咳杆菌为卵圆形短小杆菌,大小为 0.5 ~ 1.5 × 0.2 ~ 0.5um ,属鲍特氏菌属 bordetella) ,无鞭毛、芽胞。革兰氏染色阴性。用甲苯胺蓝染色可见两极异染颗粒。专性需氧,初次分离培养时营养要求较高,需用马铃薯血液甘油琼脂培养基(即鲍~金氏培养基)才能生长。经 37 ℃ 2 ~ 3 天培养后,可见细小、圆形、光滑、凸起、银灰色、不透明的菌落,周围有模糊的溶血
Bordetella pertussis causes an upper respiratory infection in infants, adolescents, and adults. Diagnosis of pertussis, a vaccine-preventable disease, can be difficult, but recent implementation of real-time PCR assays in laboratories
Bordetella pertussis , the causative agent of whooping cough, secretes a plethora of virulence factors contributing to the onset and characteristic of the disease. The exotoxin pertussis toxin (PT) is regarded as particularly important
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