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- 保存条件：
at-20℃
- 库存：
99
- 抗体英文名：
Anti-Pan-pY/pTyr/Phosphotyrosine Monoclonal antibody (SAA0305)
- 规格：
50-100ug
小鼠抗Pan-pY/pTyr/Phosphotyrosine单克隆抗体(克隆号SAA0305)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
小鼠抗Pan-pY/pTyr/Phosphotyrosine单克隆抗体(克隆号SAA0305)更多优势产品欢迎新老客户选购。
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文献和实验MS从磷酸化蛋白中检测出磷酸化肽段会遇到许多问题，这是由于样品中大量的非磷酸化肽段的存在使磷酸化肽段的相对浓度降低造成的。大量的非磷酸化肽段会抑制MS对磷酸化肽段的检测，因此必须采取额外的实验步骤在MS之前富集磷酸化蛋白或磷酸化肽段。对此，抗磷酸化特异性抗体以及亲和层析琼脂糖珠子或柱子就能起到很好得到富集作用。特别是对于细胞中比例很低的酪氨酸磷酸化的研究来说，富集的过程尤显重要。目前，通用型的抗酪氨酸磷酸化（pan-phosphotyrosine）单克隆抗体4G10和PY20已被证明对寻找蛋白酪氨酸磷酸
,2F12;CRIS-3 Leu LFA-1(gp180/95)的α链 与ICAM-1（CD54）和ICAM-2（CD102）结合 CD11b Mol,OKM1; (Mac-1,CR3,integrin αm G,M,NK gp165/95的α链 C3bi和FB受体，与ICAM-1结合，粘附，调理吞噬 CD11c LeuM5;(CR4,integrin αx) M,G,NK,Tsub gp150/95的α链 C3bi受体，调理吞噬
性因子的。 Growth factor receptor 生长因子受体，细胞表面与生长因子结合的特殊位点。 Growth suppressor 生长抑制因子，一种抑制细胞生长的生长因子。 H HAMA 人体小鼠抗体，患者被反复注射小鼠源性单克隆抗体后形成的抗体。 Haptotaxis 趋触性，趋向结合底物的化学梯度而移动的过程，是肿瘤细胞的一种移动的方式。 Heat shock protein
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