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- 保存条件：
at-20℃
- 库存：
99
- 抗体英文名：
Anti-Vaccinia virus(VACV) D8L Monoclonal antibody (LA5)
- 规格：
50-100ug
小鼠抗Vaccinia virus(VACV) D8L单克隆抗体(克隆号LA5)上海圻明生物优势供应欢迎咨询。配对抗体小课堂：
Paired antibodies are two antibodies that can bind to an antigenic molecule at the same time. Specifically:
Paired antibodies are commonly used in sandwich ELISA experiments
An antigenic molecule usually has multiple epitopes, and different antibodies can target different epitopes
When two antibodies are able to bind to different epitopes of the same antigenic molecule at the same time, the two antibodies are called paired antibodies
However, not all antibodies against different epitopes can be paired antibodies. Sometimes, when an antibody binds to an antigen, it may cause the configuration of other binding sites to change, making it impossible for other antibodies to bind properly
Steric hindrance effects may also result in two antibodies with close binding sites not being able to bind to the antigen at the same time
Therefore, the preparation of paired antibodies usually requires two steps: first the antibody is prepared, and then the paired antibody is screened
Screening of paired antibodies is typically performed using a sandwich ELISA method of bispecific antibodies, in which different combinations of antibodies are tested to determine which antibodies can be successfully paired
Paired antibodies have important applications in immunology research and diagnostics, especially in assays that require high specificity and sensitivity.
小鼠抗Vaccinia virus(VACV) D8L单克隆抗体(克隆号LA5)更多优势产品欢迎新老客户选购。
MAB1596 小鼠抗ASFV F317L单克隆抗体(克隆号1A012)
MAB1597 小鼠抗ASFV I177L单克隆抗体(克隆号1A013)
MAB1598 小鼠抗CSFV NS5B单克隆抗体(克隆号1A014)
MAB1599 小鼠抗CSFV NS5B单克隆抗体(克隆号1A015)
MAB1600 小鼠抗ASFV I10L单克隆抗体(克隆号1A016)
MAB1601 小鼠抗ASFV NS4A单克隆抗体(克隆号1A017)
MAB1602 小鼠抗ASFV NS4A单克隆抗体(克隆号1A018)
MAB1603 小鼠抗ASFV F778R单克隆抗体(克隆号1A019)
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文献和实验中科院高福院士课题组 2019 年发表了哪些重要的研究成果？
蛋白「胶合」在一起，起到稳定剂的作用。图片来源：Cell Host & Microbe该发现提供了 ASFV 衣壳结构的全面分子模型，将有助于未来对策的发展，以及推动疫苗的研发。原文链接：https://doi.org/ 10.1016 /j.chom.2019.11.004Nature Microbiology：Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus（人抗裂谷热单克隆抗体
（minor lymph'ocyte stimulating antigen,Mlsag）。 近年来证明这种内源性MLs抗原是小鼠乳腺肿瘤病毒（mouse mamary umor virus,MMTV）产生的蛋白。MMTV是一种逆转录病毒，以前病毒（provirus）形式整合于小鼠细胞DNA中。这种小鼠可终生制造这种病毒蛋白，因之可视为一种自身超抗原。这种小鼠内源性MLs抗原的化学性质现已证明是一种糖蛋白。 由于MLs抗原的来源已经清楚，故目前称这种小鼠的内源性超抗原为病毒性超抗原。人类
1~100ug，细胞抗原107个/20mL脾细胞悬液，细胞性抗原需经60Co照射或用固定剂短暂固定。可采取体内和体外联合免疫法-即体内免疫采用脾内法，腹腔或皮下多点注射2~3次。融合前加强免疫改为体外诱导法。常规方法是取免疫过的小鼠脾脏，制备脾细胞悬液，用完全培养液悬浮细胞，加入rHulL-2、rHulL-6、PWM和特异性免疫原，使其终浓度分别为50U/mL、500 U/mL、1?200和500 ug/mL，置5% CO2，37℃温箱中培养5d后，收获细胞供融合用。（二）杂交瘤选择骨髓瘤是一种抗体
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