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- 详细信息
- 技术资料
- 免疫原:
Synthesized peptide derived from human UBP18
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human, Mouse
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
1 mg/ml
- 靶点:
USP18 ISG43
- 抗体英文名:
UBP18 rabbit pAb
- 抗体名:
UBP18
- 规格:
50ul
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011],
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UBP18 rabbit pAb
¥900






