- ￥900
- AAB
- 上海
- A21235
- 2025年07月13日
- IHC-p
- Rabbit
- Human,Mouse
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- 详细信息
- 技术资料
- 免疫原：
Synthesized peptide derived from human protein . at AA range: 4291-4340
- 形态：
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
IHC-p
- 浓度：
1 mg/ml
- 靶点：
SACS KIAA0730
- 抗体英文名：
SACS rabbit pAb
- 抗体名：
Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29)
- 规格：
50ul
sacsin molecular chaperone(SACS) Homo sapiens This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al., PubMed: 19208651).
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SACS rabbit pAb
￥900
