- ￥900
- AAB
- 上海
- A20565
- 2025年07月13日
- WB,IHC-p,ELISA
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from the C-terminal region of human TNFSF11. AA range:268-317
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse,Rat
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB,IHC-p,ELISA
- 浓度：
1 mg/ml
- 靶点：
TNFSF11
- 抗体英文名：
RANKL rabbit pAb
- 抗体名：
Tumor necrosis factor ligand superfamily member 11
- 规格：
50ul
tumor necrosis factor superfamily member 11(TNFSF11) Homo sapiens This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B ly
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技术资料暂无技术资料 索取技术资料
RANKL rabbit pAb
￥900
