- ￥900
- AAB
- 上海
- A19368
- 2025年12月27日
- WB,IHC-p,IF,ELISA
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser418. AA range:384-433
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse,Rat
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB,IHC-p,IF,ELISA
- 浓度：
1 mg/ml
- 靶点：
RPS6KB1
- 抗体英文名：
p70 S6 kinase α (phospho Ser418) rabbit pAb
- 抗体名：
Ribosomal protein S6 kinase beta-1
- 规格：
50ul
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文献和实验Measurement of Phosphoinositide 3-Kinase Activity
only PtdIns as a substrate (e.g., mammalian PtdIns 3-kinase and yeast Vps34p) ( 1 ). Generally, PI 3 kinases are now regarded as an important intracellular signal upstream of a variety of biochemical (e.g., activation of Akt/protein kinase B and/or p70
of the serine/threonine kinaseAkt, which will phosphorylate GSK-3 at specific serine residues(Ser21 in GSK-3a and Ser9 in GSK-3b), leading to the inactivationof GSK-3 kinase activity (10) . However, this phosphorylationand inactivation of GSK-3 by Akt
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
a pseudo-substrate and binds to the phosphate-binding pocketon GSK3, preventing interaction with primed substrates (8) . Phosphorylation at this site is mediated by members of the AGCfamily of kinases (e.g. PKB, PKC, p70S6K, and p90RSK) andcommonly
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