- ￥900
- AAB
- 上海
- A18025
- 2025年10月22日
- IF,WB,IHC-p,ELISA
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853. AA range:621-670
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse,Rat
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
IF,WB,IHC-p,ELISA
- 浓度：
1 mg/ml
- 靶点：
PPP1R12A
- 抗体英文名：
MYPT1 (phospho Thr853) rabbit pAb
- 抗体名：
Protein phosphatase 1 regulatory subunit 12A
- 规格：
50ul
protein phosphatase 1 regulatory subunit 12A(PPP1R12A) Homo sapiens Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosph
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技术资料暂无技术资料 索取技术资料
MYPT1 (phospho Thr853) rabbit pAb
￥900
