- ￥900
- AAB
- 上海
- A16946
- 2025年09月01日
- WB,ELISA
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 技术资料
- 免疫原：
Synthesized peptide derived from human LATS1/2
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse,Rat
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB,ELISA
- 浓度：
1 mg/ml
- 靶点：
LATS1 WARTS
- 抗体英文名：
LATS1/2 rabbit pAb
- 抗体名：
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
- 规格：
50ul
large tumor suppressor kinase 1(LATS1) Homo sapiens The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen
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LATS1/2 rabbit pAb
￥900
