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- 详细信息
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from human JDP2. AA range:114-163
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human,Mouse,Rat
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
WB,ELISA
- 浓度:
1 mg/ml
- 靶点:
JDP2
- 抗体英文名:
JDP2 rabbit pAb
- 抗体名:
Jun dimerization protein 2
- 规格:
50ul
function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subunit:Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.,
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JDP2 rabbit pAb
¥900






