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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human IL1R1. AA range:31-80
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
WB,IHC-p,ELISA
- 浓度:
1 mg/ml
- 靶点:
IL1R1
- 抗体英文名:
IL-1RI rabbit pAb
- 抗体名:
Interleukin-1 receptor type 1
- 规格:
50ul
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文献和实验抗体 (ACPA) 等针对自身组织的抗体,并持续释放 TNF-α、IL-1 等大量促炎因子,从而导致滑膜出现持续性炎症,进而引发关节软骨和骨破坏[1]。类风湿性关节炎患者的关节肿胀反映了由于免疫激活而引起的滑膜炎症。 图 1. 正常关节与类风湿性关节炎关节[1]。 Section.02 RA 药物发展 在 20 世纪 90 年代初,糖皮质激素 (Cs) 或 NSAIDs (非甾体抗炎药)、是治疗类风湿关节炎的主要手段。 近几十年来,则以改善病情抗风湿药 (DMARDs
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
with studies on the pathogenesis of fever. The studies were performed by Menkin and Beeson in 1943-1948 on the fever producing properties of proteins released from rabbit peritoneal exudate Cell s. These studies were followed by contributions
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