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Please store the product under the recommended conditions in the Certificate of Analysis.
- 库存:
货期:询盘
- 供应商:
MedChemExpress LLC
- CAS号:
765899-28-3
- 规格:
5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 5 mg | 产品价格: | ¥326.0 |
|---|---|---|---|
| 规格: | 10 mg | 产品价格: | ¥517.0 |
| 规格: | 25 mg | 产品价格: | ¥931.0 |
| 规格: | 50 mg | 产品价格: | ¥1509.0 |
| 规格: | 100 mg | 产品价格: | ¥2310.0 |
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文献和实验Assessment of Drug Transporter Function Using Fluorescent Cell Imaging
(ABC) proteins, including the breast cancer resistance protein (BCRP) and multidrug resistance proteins (MDRs), actively transport structurally diverse chemicals from a number of tissues and are being increasingly cited as mediators of clinically
浓度,在宿主解毒和保护宿主免受外来物质损害方面起着重要作用,也是产生多药耐药现象的原因。ABCG2是1998年Doyle等从阿霉素耐药的MCF7乳腺癌细胞株(MCF-7/AdrVp)首次克隆出来的,因此也称为乳腺癌耐药蛋白(breast cancer resistance protein BCRP)。该蛋白含655个氨基酸,是导致哺乳类细胞耐药的三个主要转运子之一,而且可能是干细胞唯一表达的药物输出转运子,其底物包括多种抗肿瘤药,如盐酸米托蒽醌(mitoxantrone)、甲氨
Overview of Experimental Models of the Blood‐Brain Barrier in CNS Drug Discovery
(BBB). They include P‐glycoprotein (P‐gp), multidrug‐resistant protein (MRP)‐1 to MRP6 and breast cancer resistance protein (BCRP). These ATP‐binding cassette proteins transport a variety of substrates, including amino acids, sugars, drugs, toxins
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