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文献和实验and between claudin-16 levels and patient prognosis. Forced expression of claudin-16 in breast cancer cells resulted in a less aggressive phenotype and reduced in vivo tumour �volume. Claudin-16 expression was reduced in human breast cancer, particularly in patients
nM 5'biotin end-labeled siRNA under gentle agitation, i.e. a rocking plate (Figure 1a). We utilized the EF1 alpha specific siRNA, EF52, shown previously to direct TGS in human cells (Morris et al. 2004). The EF52 siRNA was constructed with a 5' biotin
9.11 Nat Commun:乳腺癌基因 GREB1 有望成为开发肝母细胞瘤靶向性疗法的潜在靶点
is associated with reduced cognitive and clinical decline in Alzheimer’s disease ③ Nature 子刊:新一代单细胞 itChIP 技术解析早期胚胎细胞命运决定机制染色质免疫共沉淀(ChIP-seq)技术是捕获蛋白质-DNA 相互作用的有效手段,然而目前单细胞 ChIP-seq 技术仍面临诸多挑战,极大限制了人们对细胞命运特化的调控机制的认识。2019 年 9 月 3 日,北京大学分子医学研究所、北大-清华生命科学联合中心何爱彬组利用一种
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