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文献和实验Live Viral Vectors: Construction of a Replication-Deficient Recombinant Adenovirus
them to express the recombinant protein. In our laboratory, successful results have been obtained using replication-deficient recombinant adenoviruses as immunizing agents for tick-borne encephalitis virus NSl protein (3 ) and measles virus nucleoprotein
Experimental autoimmune encephalomyelitis (EAE) and Theiler’s murine encephalitis virus-induced demyelinating disease (TMEV-IDD) are two clinically relevant murine models of multiple sclerosis (MS). Like MS, both are characterized by mononuclear
Mosquito-borne flavivirus RNA genomes encode one long open reading frame flanking 5′- and 3′-untranslated regions (5′- and 3′-UTRs) which contain cis -acting RNA elements playing important roles for viral RNA translation and replication
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