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文献和实验【翻译】Development trends for monoclonal antibody cancer therapeutics
were not available, general trends could be discerned. Of the unmodified mAbs with a known isotype, 77 (95%) were IgG, whereas 4 (5%) were IgM, which function primarily through CDC. The majority (80%) of the 61 IgG mAbs with human Fc regions (murine mAbs excluded
protein depends upon the species that the antibody was raised in. Protein A binds well to rabbit, cat, human, pig and guinea pig IgG as well as mouse IgG2a and IgG2b. Protein G binds strongly to IgG from cow, goat, sheep, cow, horse, rabbit and guinea pig
v468.Chapter 3 分泌型跨膜相关蛋白提纯及Wnt抑制活性
). 2. Dishevelled (Dvl)-2 primary antibody: clone 10B5 (sc-8026;Santa Cruz Biotechnology). 3. Dvl-3 primary antibody: clone 4D3 (sc-8027; Santa CruzBiotechnology). 4. Secondary antibody to use with mouse monoclonal primaryantibodies: sheep anti-mouse IgG-HRP
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