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文献和实验Detection of K-ras Mutations by a Microelectronic DNA Chip
The increased knowledge of the human genome, thanks to its sequencing and to the accumulation of data that ensue from it, prompts the characterization of disease-causing genes. Especially because of the continuing expansion of cancer-related
PKR in Innate Immunity, Cancer, and Viral Oncolysis
found in most human cells. Following activation by double stranded (ds) RNAs produced during viral replication, PKR phosphorylates the α-subunit of eukaryotic translation initiation factor (eIF) 2, causing a severe inhibititon of cellular and viral protein synthesis
Introduction of human 14-3-3 proteins
protein revealed that the neuron-specific 14-3-3-related proteins are highly conserved (60-88%)throughout eukaryotic evolution.--------------------------------------------------------------------------------The human and bovine 14-3-3 eta protein mRNAs
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