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文献和实验Introduction of human 14-3-3 proteins
The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14
The human CYP1 family consists of at least three proteins, CYP1A1, CYP1A2, and CYP1B1 (1 ), CYP1A1 is absent or present at very low levels in human liver (2 , 3 ), but its expression is readily detectable in lung (4 , 5 ). By contrast
, whereas it is absent in lung (3 ). Various fatty acids, including lauric acid (2 –4 ), are substrates for recombinant CYP4Al l. Experiments with a panel of individual cDNA-expressed P450 enzymes indicate that CYP4Al l is a major lauric acid 12-hydroxylase
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