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文献和实验A hepatitis C virus (HCV) replicon-based protease phenotyping assay has been developed that allows determining the susceptibility of a patient’s HCV protease sequence to HCV protease inhibitors. In brief, HCV protease sequences amplified
Nomenclature and Numbering of the Hepatitis C Virus
International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about the scale of HCV-related liver disease and important biological and antigenic
Expression and Purification of Hepatitis C Virus Protease from Clinical Samples
This chapter describes the procedures for production of recombinant hepatitis C virus (HCV) NS3 protease from clinical samples, which can be used in the biochemical assays to assess the impact of different drug-resistant mutations in the NS3
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