Recombinant Rat Cyclophilin-F

Local Gene Delivery of Recombinant Adenoviruses to the Rat Carotid Artery In Vivo

, where recurrence of a stenosis occurs in an abnormal blood vessel treated by angioplasty. The main animal models used to study vascular balloon injury or angioplasty are the rat carotid, the rabbit iliac, the pig coronary and carotid models, and, less frequently

Preparation of Recombinant Adenoviruses

Adenoviruses are viruses with genomes of double-stranded DNA approx 36 kb in size. There are more than 100 different serotypes that have been identified, 47 of them of human origin. Human serotypes have been grouped into six subgenera (A-F

Use of Recombinant Adenovirus for Gene Transfer into the Rat Brain: Evaluation of Gene Transfer Efficiency, Toxicity, and Inflammatory and Immune Reac

Adenovirus (Ad) vectors have been used to successfully deliver genes into a wide variety of non-central nervous system (CNS) tissues and organs in animal models of human disease and in several human phase I clinical trials (1 –