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文献和实验【Jounal club】NATURE MEDICINE: 利用蛋白组技术发现糖尿病眼底病变新机制
spectroscopy–based proteomics, we detected 117 proteins in human vitreous and elevated levels of extracellular carbonic anhydrase-I (CA-I) in vitreous from individuals with diabetic retinopathy, suggesting that retinal hemorrhage and erythrocyte lysis
The Application of the Chemical Array for Biological Study
library GLORIA (Gene Library of Osada Laboratory at RIKEN for chemical array analysis) has been established. Using the systematic platform, we detected novel inhibitors of carbonic anhydrase II. We also have shown that this screening method is useful
. Balasubramanian, Artificial chaperoning of insulin, human carbonic anhydrase and hen egg lysozyme using linear dextrin chains-a sweet route to the native state of globular proteins, FEBS Lett. 443 (1999) 215-219. 46. M. Yoshimoto, R. Kuboi, Oxidative refolding
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