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文献和实验Gene Therapy for Hypertension: Antisense Inhibition of the Renin-Angiotensin System
to be overactive in hypertension and that are proven targets of current drug treatments. These include β1-receptors, angiotensin-converting enzyme (ACE), and angiotensin type 1 receptors (AT1R). Antisense oligonucleotides are short (12-20 bases), single strands
Local Gene Delivery of Recombinant Adenoviruses to the Rat Carotid Artery In Vivo
, the dog coronary and primate saphenous or iliac models. A healthy level of skepticism exists about many of these animal models following the success of angiotensin-converting enzyme inhibitors in preventing neointima formation in the rat model
Proteasomes that Lack Endogenous USP14 and are Devoid of UB‐AMC Hydrolysis Activity Support Protocol 2: Purification of Recombinant Human USP14 from E. coli Support Protocol 3: Synthesis and Purification of Ubiquitin
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