Recombinant Clostridium Botuli

Purification of Clostridium botulinum Type A Neurotoxin

Botulinum neurotoxins produced by strains of the spore-bearing bacterium Clostridium botulinum have long been known to cause a distinctive paralytic disease in humans and animals (1 ). In recent years, injection of crystalline botulinum

Detection of Clostridium botulinum by Multiplex PCR in Foods and Feces

Clostridium botulinum is a diverse group of anaerobic spore-forming organisms that produce lethal botulinum neurotoxins (BoNT) during their growth. BoNTs cause a paralytic condition, botulism, to man and animals. The most common forms

Introduction of Recombinant DNA into Clostridium spp.

for such studies is a means of introducing recombinant DNA into individual viable cells, and the first reports of successful plasmid transformation involved use of protoplasts or L-forms (1 –4 ), or conjugal cointegrate transfer techniques