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文献和实验【求助】factor-related apoptosis inducing ligand和TNF-α
wzmchxz 求助各位战友： factor-related apoptosis inducing ligand指的是什么，它和TNF-α的关系？ 感谢您的帮助。 kern6549 你这个不完整吧，应该是tumor necrosis factor(TNF)-related apoptosis inducing ligand。 这个分子简称TRAIL，与相应受体结合后能够诱导细胞凋亡。 目前，诱导
(9 ). Because its systemic administration was shown to mediate the regression of some mouse tumors (10 ), TNF-α has attracted much attention as a potential antitumor reagent (11 ). However, the problem of its dose-dependent toxicity has been particularly apparent in human
Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
that is expressed on the surface of a cell results in the formation of a receptor proximal protein complex. This protein complex is the platform for further signaling events within the cell. In case of death receptors like TNF-related apoptosis-inducing ligand
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