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文献和实验In Vitro Reconstitution of CFTR Biogenesis and Degradation
is recognized by a large multicatalytic protease, the 26S proteasome. This proteolytic machine is formed through the ATP-dependent association of two multimeric components, the 20S proteasome and the 19S regulatory subunit. The 19S subunit recognizes
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
IV isoform 1 (COX4I1), nuclear gene encoding mitochondrial protein, mRNA 2738 NM_004890 Homo sapiens sperm associated antigen 7 (SPAG7), mRNA 618 NM_002812 Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), mRNA 942
EXAMINING THE FUNCTION OF PROTEINS AND PROTEIN NETWORKS WITH THE YEAST TWO-HYBRID SYSTEM
kinase might be created that interacts with its regulatory subunit but not its substrate; such a mutant would be expected to compete with the wild-type kinase for regulatory subunits. Another type of potential disrupter of protein interactions
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