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文献和实验Crosslinking of molecules involved in the recognition of target cells elicits natural killer (NK) cell cytotoxicity, inducing either release of preformed cytotoxic mediators via granule exocytosis, or (enhanced) expression of ligands for target
Use of Activated Natural Killer Cells for Tumor Immunotherapy in Mouse and Human
Natural killer (NK) cells are a subset of lymphocytes with a distinct morphologic appearance (large granular lymphocytes [LGLs]) and the ability to spontaneously kill virally infected or tumor targets but to spare most normal cells
Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
transfer of pathology by injecting human and mouse brain-reactive antibodies into adult mouse as well as injecting the antibody into gestating mice and transfer of antibody from dam to fetus, (5) blocking NMDAR-mediated pathogenicity in vivo, (6) evacuation
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