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文献和实验Specific gene silencing using small hairpin RNA (shRNA) constructs offer researchers the possibility to study the influence of a single protein in the metastatic process. The role of the cellular adhesion molecule CEACAM1 on tumour formation
Comparison of Immunotoxins Bearing a Single Saporin Molecule with Multiple Toxin Conjugates
molecule. In the same report, an anti-CD22 RTA-IT containing two RTA molecules was not only seven times more potent in vitro but also significantly better therapeutically in the same SCID mouse model of human lymphoma (5 ).
Single-molecule analysis of DNA replication by molecular combing
. Wash 3 x 5 minutes in 2xSSC, 50% formamide. Wash 3 x 5 minutes in 2xSSC. Wash 3 x 5 minutes in PBS/T. Proceed with step 5 of “Immunodetection ” section. Use a mouse anti-DIG antibody (Roche) instead of the anti-DNA antibody
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