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文献和实验Assaying AKT/Protein Kinase B Activity
Akt/protein kinase B (PKB) is a serine/threonine kinase that mediates many of the anabolic actions of insulin ( 1 ), as well as the growth-promoting and/or antiapoptotic effects of other growth factors, cytokines
cAMP-dependent protein kinase (PKA) is involved in various cellular functions such as cell proliferation, gene induction, and metabolism (1 ,2 ) and its regulatory subunits have been suggested as a drug target for cancer and other diseases
Translocation Assays of Protein Kinase C Activation
, and γ), the Ca2+ -independent (nPKCδ,ɛ,η,θ, and μ), and phorbol ester-insensitive (aPKCζ and ι, the human counterpart of mouse PKCλ) subfamilies. Much research on this growing family of protein kinases has concentrated on the possibility
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