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文献和实验The 3xTg-AD Mouse Model: Reproducing and Modulating Plaque and Tangle Pathology
in other cognitive domains. The molecular mechanism of disease development and progression has not yet been fully established, nor have any cures or effective, long-lasting treatments been developed. Various transgenic mouse models of AD have proven to be invaluable
Activity of the Germline-Specific Oct4-GFP Transgene in Normal and Clone Mouse Embryos
The first step in elucidating the function of a particular gene of interest involves defining its expression pattern. One way to do this is by using a reporter gene to tag the gene either in a construct (transgenesis) or in the genome (homologous
Introduction . We hope that this information will be useful to investigators who are unfamiliar with mouse breeding or who are breeding transgenic or gene targeted mice for the first time. These suggestions are based on our experience
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