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文献和实验Assay of Anti-Endotoxin Antibodies
the endotoxin of Gram-negative bacteria. In mammals, including humans, LPS exhibits a variety of biological effects that may be beneficial if administered in low amounts but harmful when present in higher concentrations as in the case of Gram-negative infection
Purification of Endotoxin Free mAbs
1) Endotoxin - you must assume that all standard laboratory glassware will be coated with loads of endotoxin. Wherever possible use sterile, specifically endotoxin-free (clinical grade) disposable plastics. If you need to use glassware or other materials
Protein Therapeutics: Mouse, Humanized, and Human Antibodies
component of the vertebrate immune system. Each plasma cell secretes a single clone of antibodies that bind a unique epitope of an antigen. Cooperations exist between antibodies and other immune effectors such as macrophages and complement to facilitate
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