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文献和实验Analysis of the Protein S Gene in Protein S Deficiency
Protein S (PS) is a 71-kDa vitamin K-dependent glycoprotein first identified in human plasma by DiScipio and colleagues in 1977 (1 ), a year after the discovery of the anticoagulant protein C (PC) (2 ,3 ). A few years later, Walker
Protein thiol groups are susceptible to oxidation by reactive oxygen species (1 ). The occurrence of a specific thiol modification named protein S-glutathionation has been proposed to protect proteins from oxidative damage owing
Characterization and Use of Monoclonal Antibodies to Tau and Paired Helical FilamentTau
Antibodies to the microtubule-associated protein tau have been used for more than a decade, both in studies of the role of tau neuronal function, and in examination of the neurofibrillary pathology of Alzheimer’s disease (AD). The vast majority
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