- ￥900
- AAB
- 上海
- A14489
- 2025年07月12日
- WB
- Rabbit
- Human, Mouse
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- 详细信息
- 技术资料
- 免疫原：
Synthesized peptide derived from human FBW1A
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human, Mouse
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1 mg/ml
- 靶点：
BTRC BTRCP FBW1A FBXW1A
- 抗体英文名：
FBW1A rabbit pAb
- 抗体名：
FBW1A
- 规格：
50ul
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012],
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FBW1A rabbit pAb
￥900
