- ￥900
- AAB
- 上海
- A14776
- 2025年07月08日
- WB,IHC-p,ELISA
- Rabbit
- Human,Mouse,Monkey
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- 详细信息
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436. AA range:402-451
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse,Monkey
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB,IHC-p,ELISA
- 浓度：
1 mg/ml
- 靶点：
FRS2
- 抗体英文名：
FRS2 (phospho Tyr436) rabbit pAb
- 抗体名：
Fibroblast growth factor receptor substrate 2
- 规格：
50ul
function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence caution:Translated as stop.,similarity:Contains 1 IRS-type PTB domain.,subcellular location:Cytoplasmic, membrane-bound.,subunit:Part of a complex containing FRS2, GRB2 and SOS1. Part of a complex containing GRB2 and CBL. Binds RET (By similarity). Binds FGFR1, SUC1, NTRK1, NTRK2, NTRK3 and SRC. The tyrosine-phosphorylated protein binds the SH2 domains of GRB2 and PTPN11.,tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.,
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FRS2 (phospho Tyr436) rabbit pAb
￥900
