- ￥900
- AAB
- 上海
- A13710
- 2025年07月07日
- WB,IHC-p,IF,ELISA
- Rabbit
- Human,Mouse
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- 详细信息
- 技术资料
- 免疫原：
The antiserum was produced against synthesized peptide derived from human DOK4. AA range:11-60
- 形态：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件：
-20°C/1 year
- 克隆性：
Polyclonal
- 适应物种：
Human,Mouse
- 保质期：
1年
- 宿主：
Rabbit
- 应用范围：
WB,IHC-p,IF,ELISA
- 浓度：
1 mg/ml
- 靶点：
DOK4
- 抗体英文名：
Dok-4 rabbit pAb
- 抗体名：
Docking protein 4
- 规格：
50ul
domain:PTB domain mediates receptor interaction.,function:DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.,PTM:Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation.,similarity:Belongs to the DOK family. Type B subfamily.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain.,subunit:Interacts with RET and TEK/TIE2. Interaction with RET is mediated through the PTB domain and requires phosphorylation of RET 'Tyr-1062'.,tissue specificity:Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells.,
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Dok-4 rabbit pAb
￥900
