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- 详细信息
- 技术资料
- 免疫原:
The antiserum was produced against synthesized peptide derived from human Cyclin D1. AA range:246-295
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Polyclonal
- 适应物种:
Human,Mouse,Rat
- 保质期:
1年
- 宿主:
Rabbit
- 应用范围:
IF,WB,IHC-p,ELISA
- 浓度:
1 mg/ml
- 靶点:
CCND1
- 抗体英文名:
Cyclin D1 rabbit pAb
- 抗体名:
G1/S-specific cyclin-D1
- 规格:
50ul
cyclin D1(CCND1) Homo sapiens The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008],
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Cyclin D1 rabbit pAb
¥900







