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Bag-4 rabbit pAb

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  • ¥900
  • AAB
  • 上海
  • A11116
  • 2025年07月15日
  • WB,IHC-p,ELISA
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthesized peptide derived from the C-terminal region of human Bag-4.

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse,Rat

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      BAG4

    • 抗体英文名

      Bag-4 rabbit pAb

    • 抗体名

      BAG family molecular chaperone regulator 4

    • 规格

      50ul

    BCL2 associated athanogene 4(BAG4) Homo sapiens The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct

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    图标文献和实验
    相关实验
    • Immunochemical Detection of a Fluorophore Derived from the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Lysine

      = NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific

    • Western Blots

      -hot polyclonal, or 1:30 dilution of tissue culture supernatant for a good monoclonal. Do the incubation in a sealameal bag for 1 hr at room temp on a rocker. Can go overnight in the fridge. Remember: it's critical to do a control with no 1° antibody

    • Western Blotting Protocols

        Required Equipment Shallow trays, large enough to hold blot Glass plates Plastic wrap (e.g., Saran™ film), freezer bag, or sheet protector Autoradiography film and cassette Dark room Autoradiography film

    图标技术资料

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