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- 详细信息
- 技术资料
- 免疫原:
Recombinant Protein of ATM of ATM
- 形态:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 保存条件:
-20°C/1 year
- 克隆性:
Monoclonal
- 适应物种:
Human,Rat,Mouse
- 保质期:
1年
- 宿主:
Mouse
- 应用范围:
IHC-p
- 浓度:
1 mg/ml
- 靶点:
ATM
- 抗体英文名:
ATM mouse mAb(3D3)
- 抗体名:
ATM
- 规格:
50ul
ATM serine/threonine kinase(ATM) Homo sapiens The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],
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ATM mouse mAb(3D3)
¥900






