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Ataxin-1 (phospho Ser776) rabb

it pAb
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  • ¥900
  • AAB
  • 上海
  • A10934
  • 2025年07月12日
  • WB,IHC-p,IF,ELISA
  • Rabbit
  • Human,Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      The antiserum was produced against synthesized peptide derived from human Ataxin 1 around the phosphorylation site of Ser776. AA range:742-791

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,IF,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      ATXN1

    • 抗体英文名

      Ataxin-1 (phospho Ser776) rabbit pAb

    • 抗体名

      Ataxin-1

    • 规格

      50ul

    ataxin 1(ATXN1) Homo sapiens The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted

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    图标文献和实验
    相关实验
    • Regulation of Ataxin-1 Phosphorylation and Its Impact on Biology

      Ataxin-1 protein expression is found in the cytoplasm and nucleus of Purkinje cells, the primary site of spinocerebellar ataxia type 1 (SCA1). Phosphorylation at S776 occurs in the cytoplasm and stabilizes the protein through interaction

    • 组化染色背景高?没信号?一篇文章带你快速掌握免疫组化!

      :使用 Anti-phospho-Akt (Ser473) Rabbit mAb 对石蜡包埋的人乳腺癌组织进行免疫组织化学分析。(图 A)使用免疫组化试剂盒M&R HRP/DAB Detection IHC Kit,抗体 1:100 稀释;(图 B) 采用普通免疫组化试剂盒,抗体 1:25 稀释。 图 6 免疫组化实验检测 Erk1/2 表达 注:使用 Anti-Erk1/2 Mouse mAb与p44/42 MAPK (Erk1/2)Rabbit mAb 对正常小鼠心脏组织进行免疫

    • v468 chapter 5 糖原合成酶激酶-3 的抑制

      at 10, 25, and 50 μM). At 24 h post-treatment, celllysates were obtained; SDS-PAGE and Western blotting were performed as described in Section 3, Methods. AR-A014418dose-dependent decreases of phospho-β-catenin (Ser33/37) and phospho-glycogen synthase

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