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ASK 1 (phospho Ser966) rabbit

pAb
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  • ¥900
  • AAB
  • 上海
  • A10906
  • 2025年07月10日
  • WB,IHC-p,ELISA
  • Rabbit
  • Human,Mouse,Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      The antiserum was produced against synthesized peptide derived from human ASK1 around the phosphorylation site of Ser966. AA range:932-981

    • 形态

      Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

    • 保存条件

      -20°C/1 year

    • 克隆性

      Polyclonal

    • 适应物种

      Human,Mouse,Rat

    • 保质期

      1年

    • 宿主

      Rabbit

    • 应用范围

      WB,IHC-p,ELISA

    • 浓度

      1 mg/ml

    • 靶点

      MAP3K5

    • 抗体英文名

      ASK 1 (phospho Ser966) rabbit pAb

    • 抗体名

      Mitogen-activated protein kinase kinase kinase 5

    • 规格

      50ul

    mitogen-activated protein kinase kinase kinase 5(MAP3K5) Homo sapiens Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by Re

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