- ￥10600 - 17500
- TargetMol
- 美国
- T69983
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Ixazomib citrate EtOH
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2026591-78-4
- 规格：
50 mg/100 mg/25 mg
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
Product Introduction
Bioactivity
英文名:Ixazomib citrate EtOH
描述:Ixazomib citrate, also known as MLN9708, is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. MLN9708, after hydrolyzing to pharmacologically active MLN2238 (ixazomib), is a next-generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity. MLN9708, compared with bortezomib, has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies.
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文献和实验Yeast Prep for FACS [Adapted from Nash et al. EMBO , 7(13):4335-4346; 1988.] 1. Spin down 1E7 cells in a microfuge tube for 1 minute. 2. Resuspend pellet in 1 ml of 70% EtOH. Fix for at least 60 minutes at room temperature
In Situ Cell Death (Apoptosis) Detection by TUNEL labeling
150ml 4% Paraformaldehyde/1x PBS to RT. Fix slides in it, 20 min., RT. 1x PBS rinse, 2 times. 1x PBS, 30 min., RT. Begin chilling Triton/SSC on ice. 0.1% Triton/ 0.1% Sodium Citrate, 2 min., 4°C. All slides: 1x PBS rinse
ml 4% Paraformaldehyde/1x PBS to RT. Fix slides in it, 20 min., RT. 1x PBS rinse, 2 times. 1x PBS, 30 min., RT. Begin chilling Triton/SSC on ice. 0.1% Triton/ 0.1% Sodium Citrate, 2 min., 4°C. All slides: 1x PBS rinse, 2 times
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