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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
NIK-12192
- 库存:
10
- 供应商:
TargetMol
- CAS号:
318262-42-9
- 规格:
50 mg/25 mg/100 mg
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
Product Introduction
Bioactivity
英文名:NIK-12192
描述:NIK-12192 is an indole derivative and inhibitor of vacuolar-H(+)-ATPase.

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文献和实验Identification of Peptide Features in Precursor Spectra Using Hardklör and Krönik
Abstract Table of Contents Figures Literature Cited Abstract Hardklör and Krönik are software tools
factor 2 (TRAF-2) that recruits NF-kB-inducible kinase (NIK). Both IKK1 and IKK2 have canonical sequences that can be phosphorylated by the MAP kinase NIK/MEKK1 and both kinases can independently phosphorylate IkBa or IkBb. TRAF-2 also interacts with A20
and p38. Activation of the NFkappB pathway is complex. It requires activation of phosphatidylinositol-3-kinase (PI3K) upstream of IkappaBalpha degradation. A second NFkappaB activation pathway follows the sequence: TLR4, MyD88, TIR, IRAK1, TRAF6, NIK, IKK
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