- ￥287 - 1653
- TargetMol
- 美国
- T67847
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Imatinib impurities3
- 库存：
10
- 供应商：
TargetMol
- CAS号：
404844-11-7
- 规格：
50 mg/25 mg/10 mg/100 mg/5 mg
| 规格： | 50 mg | 产品价格： | ￥1098.0 |
|---|---|---|---|
| 规格： | 25 mg | 产品价格： | ￥735.0 |
| 规格： | 10 mg | 产品价格： | ￥427.0 |
| 规格： | 100 mg | 产品价格： | ￥1653.0 |
| 规格： | 5 mg | 产品价格： | ￥287.0 |
Product Introduction
Bioactivity
英文名:Imatinib impurities3
描述:Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for ABL1 wt, KIT wt, PDGFRR wt, respectively.
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文献和实验that there are some impurities that could be produced during synthesis or during storage of the drug. Consequently, there is great interest in the analysis of the drug and its impurities. HPLC (7 ) or capillary electrophoresis (8 ) methods have been used to determine
Detection of BCR-ABL Mutations and Resistance to Imatinib Mesylate
The major mechanism of imatinib resistance for patients with chronic myeloid leukemia (CML) is clonal expansion of leukemic cells with mutations in the Bcr-Abl fusion tyrosine kinase that reduce the capacity of imatinib to inhibit kinase
and quantitate the tumor-specific BCR-ABL1 RNA have been shown to be an ultrasensitive diagnostic, prognostic, and monitoring tool for Philadelphia-positive leukemias. A novel tyrosine kinase inhibitor (TKI), imatinib, has been confirmed as an effective targeted
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