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- 美国
- T67706
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
mTOR inhibitor 9c
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1144075-36-4
- 规格：
1 mg/10 mg/25 mg/100 mg/5 mg/50 mg
| 规格： | 1 mg | 产品价格： | ￥2300.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥7790.0 |
| 规格： | 25 mg | 产品价格： | ￥11500.0 |
| 规格： | 100 mg | 产品价格： | ￥20800.0 |
| 规格： | 5 mg | 产品价格： | ￥5570.0 |
| 规格： | 50 mg | 产品价格： | ￥15600.0 |
Product Introduction
Bioactivity
英文名:mTOR inhibitor 9c
描述:mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for mTOR and PI3Kα, respectively.
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文献和实验The mammalian target of rapamycin (mTOR) is the catalytic subunit of two multiprotein complexes, mTOR complex-1 (mTORC1) and mTOR complex-2 (mTORC2). Clinically used rapamycin and rapalogs are FKBP12-dependent allosteric inhibitors of mTORC
Expanding Human T Regulatory Cells with the mTOR-Inhibitor Rapamycin
CD4+ CD25+ FOXP3+ T regulatory (Treg) cells are pivotal for the induction and maintenance of peripheral tolerance in both mice and humans. The possibility to use Treg cells for the treatment of T-cell-mediated diseases has recently gained
Development of ATP-Competitive mTOR Inhibitors
mTOR inhibitor rapamycin and structurally related rapalogs have failed to show significant single-agent antitumor efficacy in most types of cancer. This limited clinical success may be due to the inability of the rapalogs to maintain a complete blockade
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