- ￥10600 - 17500
- TargetMol
- 美国
- T63522
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Anticancer agent 64
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2387902-92-1
- 规格：
50 mg/25 mg/100 mg
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
|---|---|---|---|
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
Product Introduction
Bioactivity
英文名:Anticancer agent 64
描述:Anticancer agent 64 (compound 5m) demonstrates effective cytotoxic activity against CCRF-CEM cells, exhibiting an IC50 value of 2.4 μM. It effectively induces apoptosis in cancer cells by activating caspase 3 and 7 and causing PARP cleavage. Additionally, it significantly disrupts mitochondrial membrane potential, contributing to its anticancer efficacy [1].
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文献和实验了莱姆病。这组作者还从一只未被感染的实验小鼠身上的虱子获取了这种经过遗传修饰的细菌并且重新培养，然后为另一组没有莱姆病的小鼠进行了注射。这组作者说，所有接受注射的小鼠感染了该病，显示出bba64基因很可能对于让虱子仅仅通过叮咬而感染宿主是必不可少的。 这组科学家提出，阻断bba64基因可能带来一种开发莱姆病疫苗的新策略。 点击此处下载原文 The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical
Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignancies
The role of protein tyrosine kinases (PTKs) in the survival of cancer cells and their potential use in anticancer therapy has led to their selection as anticancer drug targets. Tyrosine kinases which are being studied for this purpose include
Immunosuppressors as Multidrug Resistance Reversal Agents
of anticancer agent-induced apoptosis. In fact, CSA and PSC833 are also able to respectively inhibit ceramide glycosylation and stimulate de novo ceramide synthesis. This could enhance the cellular level of ceramide and potentiate apoptosis induced
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