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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
OXPHOS-IN-1
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2749554-48-9
- 规格:
100 mg/25 mg/50 mg
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
Product Introduction
Bioactivity
英文名:OXPHOS-IN-1
描述:OXPHOS-IN-1 (compound 2) is an inhibitor of oxidative phosphorylation (OXPHOS) and inhibits the growth of MIA PaCa-2 cells (IC50: 2.34 μM) and BxPC-3 cells (IC50: 13.82 μM).

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文献和实验flow coupled to proton pumping to compensate for proton leaks) and ETS capacity. If OXPHOS capacity (maximally ADP-stimulated oxygen flux) is less than ETS capacity, the phosphorylation system contributes to flux control. Physiological Complex I + II
(OXPHOS). Maintenance of energy homeostasis under most physiological conditions is therefore contingent upon the ability of OXPHOS to meet cellular changes in bioenergetic demand, with a chronic failure to do so being a frequent cause of human disease
Biochemical Analyses of the Electron Transport Chain Complexes by Spectrophotometry
In the diagnostic work-up of patients with suspected mitochondrial disease, evaluating the activity of the individual oxidative phosphorylation (OXPHOS) complexes is crucial. Here, we describe spectrophotometric assays for OXPHOS enzymology
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