- ￥14900 - 24625
- TargetMol
- 美国
- T62517
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
S1p receptor agonist 2
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1354908-17-0
- 规格：
100 mg/25 mg/50 mg
| 规格： | 100 mg | 产品价格： | ￥24625.0 |
|---|---|---|---|
| 规格： | 25 mg | 产品价格： | ￥14900.0 |
| 规格： | 50 mg | 产品价格： | ￥19420.0 |
Product Introduction
Bioactivity
英文名:S1p receptor agonist 2
描述:S1p receptor agonist 2 (compound 1) is an agonist of the S1P5 receptor with a higher selectivity than S1P1 and/or S1P3 receptors.S1p receptor agonist 2 can be used in the endogenous SIP signaling system and in the mitigation/prevention of central nervous system (CNS) diseases such as neurodegenerative diseases. .
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文献和实验Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization
to agonist-dependent regulation. In the case of the μ-opioid receptor (MOPr), we have shown that two agonists, morphine and the peptide agonist DAMGO, can induce MOPr desensitization by different mechanisms involving largely protein kinase C
expressing the individual S1P1–5 receptor subtypes. The cells are grown in 96-well plates and loaded with the cell permeable fluorescent Ca2+ indicator dye Fura-2-AM. Changes in intracellular Ca2+ levels in response to S1P or test compounds are detected using
PPAR/ Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells
an important role in the effort to help extend its dismal 5-year survival rate (2 (PGE2 ), and the prostag-landin E2 receptor subtype, EP4, promote the growth and progression of human nonsmall cell lung carcinoma (NSCLC), the most common lung carcinoma
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