- ￥10600 - 17500
- TargetMol
- 美国
- T62284
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Anti-inflammatory agent 21
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2408836-40-6
- 规格：
100 mg/50 mg/25 mg
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
Product Introduction
Bioactivity
英文名:Anti-inflammatory agent 21
描述:Anti-inflammatory agent 21 (compound 9o) is a low cytotoxic, orally active anti-inflammatory agent that acts on NO (IC50: 0.76 μM). Anti-inflammatory agent 21 is able to accumulate ROS and block NF-κB/MAPK signaling pathway to exert anti-inflammatory effects. Anti-inflammatory agent 21 has a beneficial effect on cartilage destruction and inflammatory cell infiltration in a rat model of arthritis.
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文献和实验Chemoprevention of Lung Cancer
and non steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for colon cancer“ (1 ). This somewhat pessimistic statement reflects the outcome of several clinical trials that examined whether human lung cancer could effectively be prevented
, double-stranded RNA molecules by an enzyme called DICER, which cleaves RNA duplexes into 21–26 base-pair oligomers. These small interfering RNAs (siRNA) cause sequence-specific post-transcriptional gene silencing by guiding an endonuclease, the RNAi
Chemical Induction of Apoptosis
agents such as doxorubicin, 5-fluorouracil, paclitaxel or vinblastine. A typical time course for p53 and p21WAF1 induction is 40 to 48 hours treatment with a DNA damaging agent. Other proteins involved in apoptosis are also induced
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