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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
γ-Secretase modulator 13
- 库存:
10
- 供应商:
TargetMol
- CAS号:
1353570-40-7
- 规格:
5 mg/1 mg/50 mg/100 mg/25 mg/10 mg
| 规格: | 5 mg | 产品价格: | ¥4920.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1980.0 |
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 10 mg | 产品价格: | ¥7130.0 |
Product Introduction
Bioactivity
英文名:γ-Secretase modulator 13
描述:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that inhibits the production of amyloid β-peptide Aβ42 and can be used to study Alzheimer's disease and tumors.

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文献和实验Protein Kinase C as a Modulator of 5- HT1A and Dopamine- D2 Receptor Signaling
, 1995 ), its translocation to the membrane (Kiley et al., 1995 ), and the phosphorylation of numerous proteins. With the finding by Castagna et al. (1982) that phorbol esters (e.g., 12-O-tetrade-canoyl 4β-phorbol 13-acetate [TPA]) are potent
T cells的分类及肿瘤特性[2] γδ T细胞的“两面性” γδ T细胞可通过直接或间接的方式起到抗肿瘤的目的。首先,γδ T细胞迁移到肿瘤局部环境后,可通过穿孔素-颗粒酶途径溶解癌细胞[8];其次,γδ T细胞可以通过配体TRAIL和FasL消灭癌细胞[9,10]。另外,γδ T细胞还可以通过ADCC来杀死癌细胞。γδ T细胞也是IFN-γ和TNF-α重要的早期来源[11,12]。IFN-γ和TNF-α均通过多种机制抑制癌症的生长[13]。除此之外,γδ T细胞可分
Determining the Activation of Rho as an Index of Receptor Coupling to G12/13 Proteins
Heterotrimeric G proteins are composed of α, β, and γ subunits. G proteins can be activated by a large number of cell-surface hepathelical receptors and can transduce signals from these receptors to various intracellular signaling molecules
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