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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
CHIKV-IN-3
- 库存:
10
- 供应商:
TargetMol
- 规格:
50 mg/25 mg/100 mg
| 规格: | 50 mg | 产品价格: | ¥13800.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥10600.0 |
| 规格: | 100 mg | 产品价格: | ¥17500.0 |
Product Introduction
Bioactivity
英文名:CHIKV-IN-3
描述:CHIKV-IN-3 is a potent inhibitor effective against two low-passage CHIKV strains, demonstrating EC50 values of 1.55 μM for CHIKV-122508 and 0.14 μM for CHIKV-6708, respectively. It operates by targeting host cells to disrupt viral replication, while maintaining a minimal cytotoxic liability (CC50 > 100 μM). Additionally, CHIKV-IN-3 has shown a prophylactic effect [1].

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文献和实验Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus that has already infected millions of people in recent large-scale epidemics in Africa, the islands of the Indian Ocean, South and Southeast Asia, and northern Italy. The infection
A Mouse Model of Chikungunya Virus with Utility in Antiviral Studies
Chikungunya virus (CHIKV) infection generally causes a debilitating arthritis in infected patients. Infection with CHIKV is generally not life-threatening and is associated with a mortality rate
中科院高福院士课题组 2019 年发表了哪些重要的研究成果?
Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein(甲病毒受体 MXRA8 与基孔肯雅病毒包膜蛋白结合的分子基础)虫源性甲病毒,如基孔肯雅病毒 (CHIKV),可在全世界范围内引起严重和使人衰弱的风湿病,造成严重的经济损失。之前的研究发现 MXRA8 是病毒进入细胞的受体。在这里,研究人员揭示了小鼠 MXRA8、人 MXRA8 与 CHIKV E 蛋白复合物的晶体结构,以及人 MXRA8 和 CHIKV 病毒样颗粒的冷冻
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