- ￥10600 - 17500
- TargetMol
- 美国
- T61173
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Metallo-β-lactamase-IN-5
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1417737-65-5
- 规格：
50 mg/100 mg/25 mg
| 规格： | 50 mg | 产品价格： | ￥13800.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥17500.0 |
| 规格： | 25 mg | 产品价格： | ￥10600.0 |
Product Introduction
Bioactivity
英文名:Metallo-β-lactamase-IN-5
描述:Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactamase-IN-5 effectively inhibits HUVECs. Additionally, when combined with Imipenem, Metallo-β-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
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文献和实验Rapid Characterization of -Lactamases by Multiplex PCR
The rising prevalence of the members of the Enterobacteriaceae, Pseudomonas spp. and Acinetobacter baumannii that produce extended-spectrum β-lactamases (ESBLs) and carbapenem-hydrolysing β-lactamases (carbapenemases) represents
cleavage of cell surface-bound anthrax toxin protective antigen for its capacity to translocate an anthrax toxin lethal factor-β-lactamase fusion protein to the cytoplasm. A fluorogenic β-lactamase substrate is then used to visualize the cytoplasmically
of interest, and the known or putative partner protein fused to mature TEM-1 β-lactamase. The efficiency with which co-localized β-lactamase chimeras are exported in the periplasm, and thus confer ampicillin resistance to cells, is directly linked to the relative binding
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